自治医科大学 分子病態研究部 - 生体分子イメージング手法を組み入れた生活習慣病(肥満・糖尿病・血栓止血領域等)を対象とした基礎研究部門

自治医科大学
分子病態治療研究センター

分子病態研究部

西村研究室

〒329-0498
栃木県下野市薬師寺3311-1


TEL: 0285(58)7397(受付)
FAX: 0285(44)7817


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研究成果/業績リスト

HOME » 研究成果/業績リスト
2014年度

ENPP2 contributes to adipose Tissue expansion and insulin resistance in diet-induced obesity.

Nishimura S, Nagasaki M, Okudaira S, Aoki J, Ohmori T, Ohkawa R, Nakamura K, Igarashi K, Yamashita H, Eto K, Uno K, Hayashi N, Kadowaki T, Komuro I, Yatomi Y, Nagai R.

Diabetes. 2014; 63(12): 4154-64.

Paxillin is an intrinsic negative regulator of platelet activation in mice.

Sakata A, Ohmori T, Nishimura S, Suzuki H, Madoiwa S, Mimuro J, Kario K, Sakata Y.

Thromb J. 2014; 12(1): 1.

Combination of thrombin-antithrombin complex, plasminogen activator inhibitor-1, and protein C activity for early identification of severe coagulopathy in initial phase of sepsis: a prospective observational study.

Koyama K, Madoiwa S, Nunomiya S, Koinuma T, Wada M, Sakata AOhmori T, Mimuro J, Sakata Y.
Crit Care. 2014; 18(1): R13.

Expandable Megakaryocyte Cell Lines Enable Clinically Applicable Generation of Platelets from Human Induced Pluripotent Stem Cells.

Nakamura S, Takayama N, Hirata S, Seo H, Endo H, Ochi K, Fujita K, Koike T, Harimoto K, Dohda T, Watanabe A, Okita K, Takahasi N, Sawaguchi A, Yamanaka S, Nakauchi H, Nishimura S, Eto K. 

Cell Stem Cell. 2014; 14(4): 535-48.

Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis.

Tanaka M, Ikeda K, Suganami T, Komiya C, Ochi K, Shirakawa I, Hamaguchi M, Nishimura S, Manabe I, Matsuda T, Kimura K, Inoue H, Inagaki Y, Aoe S, Yamasaki S, Ogawa Y.

Nat Commun. 2014; 5: 4982.

Simultaneous downregulation of KLF5 and Fli1 is a key feature underlying systemic sclerosis.

Noda S, Asano Y, Nishimura S, Taniguchi T, Fujiu K, Manabe I, Nakamura K, Yamashita T, Saigusa R, Akamata K, Takahashi T, Ichimura Y, Toyama T, Tsuruta D, Trojanowska M, Nagai R, Sato S.
Nat Commun. 2014; 5: 5797.

Estrogen dependence of PDE5 inhibitor efficacy in female heart disease.

Sasaki H, Nagayama T, Blanton RM, Seo K, Zhang M, Zhu G, Lee DI, Bedja D, Hsu S, Tsukamoto O, Takashima S, Kitakaze M, Mendelsohn ME, Karas RH, Kass DA, Takimoto E.

J Clin Invest. 2014; 124(6): 2464-2471.

TUBB1 mutation disrupting microtubule assembly impairs proplatelet formation and results in congenital macrothrombocytopenia.

Kunishima S, Nishimura S, Suzuki H, Imaizumi M, Saito H.

Eur J Haematol. 2014; 92(4): 276-82.