自治医科大学 分子病態研究部 - 生体分子イメージング手法を組み入れた生活習慣病(肥満・糖尿病・血栓止血領域等)を対象とした基礎研究部門

自治医科大学
分子病態治療研究センター

分子病態研究部

西村研究室

〒329-0498
栃木県下野市薬師寺3311-1


TEL: 0285(58)7397(受付)
FAX: 0285(44)7817


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研究成果/業績リスト

HOME » 研究成果/業績リスト
2008以前年度

In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue.

Nishimura S, Manabe I, Nagasaki M, Seo K, Yamashita H, Hosoya Y, Ohsugi M, Tobe K, Kadowaki T, Nagai R, Sugiura S.

J Clin Invest. 2008; 118(2): 710-21.

Responses of single-ventricular myocytes to dynamic axial stretching.

Nishimura S, Seo K, Nagasaki M, Hosoya Y, Yamashita H, Fujita H, Nagai R, Sugiura S.

Prog Biophys Mol Biol. 2008; 97(2-3): 282-97.

Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels.

Nishimura S, Manabe I, Nagasaki M, Hosoya Y, Yamashita H, Fujita H, Ohsugi M, Tobe K, Kadowaki T, Nagai R, Sugiura S.

Diabetes. 2007; 56(6): 1517-26.

Microtubules modulate the stiffness of cardiomyocytes against shear stress.

Nishimura S, Nagai S, Katoh M, Yamashita H, Saeki Y, Okada J, Hisada T, Nagai R, Sugiura S.

Circ Res. 2006; 98(1): 81-7.

Carbon fiber technique for the investigation of single-cell mechanics in intact cardiac myocytes.

Sugiura S, Nishimura S, Yasuda S, Hosoya Y, Katoh K.

Nat Protoc. 2006; 1(3): 1453-7.

Membrane potential of rat ventricular myocytes responds to axial stretch in phase, amplitude and speed-dependent manners.

Nishimura S, Kawai Y, Nakajima T, Hosoya Y, Fujita H, Katoh M, Yamashita H, Nagai R, Sugiura S.

Cardiovasc Res. 2006; 72(3): 403-11.

Expression of green fluorescent protein impairs the force-generating ability of isolated rat ventricular cardiomyocytes.

Nishimura S, Nagai S, Sata M, Katoh M, Yamashita H, Saeki Y, Nagai R, Sugiura S.

Mol Cell Biochem. 2006; 286(1-2): 59-65.

Contractile dysfunction of cardiomyopathic hamster myocytes is pronounced under high load conditions.

Nishimura S, Yamashita H, Katoh M, Yamada KP, Sunagawa K, Saeki Y, Ohnuki Y, Nagai R, Sugiura S.

J Mol Cell Cardiol. 2005; 39(2): 231-9.

Three-dimensional simulation of calcium waves and contraction in cardiomyocytes using the finite element method.

Okada J, Sugiura S, Nishimura S, Hisada T.

Am J Physiol Cell Physiol. 2005; 288(3): C510-22.

Single cell mechanics of rat cardiomyocytes under isometric, unloaded, and physiologically loaded conditions.

Nishimura S, Yasuda S, Katoh M, Yamada KP, Yamashita H, Saeki Y, Sunagawa K, Nagai R, Hisada T, Sugiura S.

Am J Physiol Heart Circ Physiol. 2004; 287(1): H196-202.

Unloaded shortening increases peak of Ca2+ transients but accelerates their decay in rat single cardiac myocytes.

Yasuda S, Sugiura S, Yamashita H, Nishimura S, Saeki Y, Momomura S, Katoh K, Nagai R, Sugi H.

Am J Physiol Heart Circ Physiol. 2003; 285(2): H470-5.